Scleroderma is a rare disease in which a person’s immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, and internal organs-especially the esophagus, kidneys, and digestive tract-is replaced with scar tissue. This change causes the tissues to become stiff and the muscles to not work as well.
ByHealthwise Staff Primary Medical ReviewerAdam Husney, MD – Family Medicine Martin J. Gabica, MD – Family Medicine Kathleen Romito, MD – Family Medicine Specialist Medical ReviewerPeter J. Kahrilas, MD – Gastroenterology