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What is eosinophilic esophagitis? Esophagitis (say "ee-sof-uh-JY-tus") is irritation or inflammation the esophagus. This is the tube that carries food from your throat to your stomach. In eosinophilic (say "ee-uh-sin-uh-FILL-ick") esophagitis, the irritation is caused by white blood cells called eosinophils in the...