Bile Acid TUDCA Enhances Insulin Clearance & Liver Health in Obese Mice

Here, we demonstrated that 15 days treatment with TUDCA reestablished plasma insulin to physiological concentrations in high fat diet (HFD) mice, a phenomenon associated with increased insulin clearance and liver IDE expression. This effect is probably due to increased IDE expression in the liver. TUDCA treatment reduced body and fat pad weight in the HFD...