clinicopathological and molecular characteristics of synchronous gastric adenocarcinoma and gastrointestinal stromal tumors

Exon 11 mutation of c-kit is more common than mutations in exons 9, 12, 13, 14, 17 and 18. Here, we present six patients with synchronous gastric adenocarcinoma with GIST. Full size image Paraffin-embedded tissue specimens for all six synchronous adenocarcinomas with GISTs and GISTs alone were screened for mutations in c-kit and PDGFR-α. Two...