mir 16 and mir 103 impact 5 ht4 receptor signalling and correlate with symptom profile in irritable bowel syndrome

(A) HTR4 isoforms HTR4a, HTR4b, HTR4d, HTR4g, HTR4i and HTR4c, without a specified 3′UTR. Our specific aims were to locate SNPs residing within the 3′UTRs of GI-relevant HTR4 isoforms in order to identify putatively regulating miRNAs and to assess miRNA expression in gut biopsies of IBS patients compared to healthy controls and to validate the...