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Epocrates, Inc.
by Epocrates, Inc.
Epocrates, Inc. is an electronic health record (EHR) and practice management solution for ambulatory care settings. The system supports outpatient documentation, scheduling, billing, and patient engagement for physician practices and clinics.
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Markets: Physician practices · Outpatient clinics · Specialty practices · Multi-provider groups
Deployment: cloud
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Founder & CEO
Epocrates, Inc. is an electronic health record (EHR) and practice management solution for ambulatory care settings. The system supports outpatient documentation, scheduling, billing, and patient engagement for physician practices and clinics.
Pricing
Pricing model
Product source
Platform Overview
What is Epocrates, Inc.?
Epocrates, founded in 1998 and acquired by athenahealth in 2013, operates primarily as a clinical decision support and drug reference platform rather than a traditional full-service EMR/EHR system. The platform serves over 1 million healthcare providers across the United States, making it one of the most widely adopted mobile medical reference applications in the market. Epocrates specializes in point-of-care clinical information, drug interaction checking, formulary verification, and prescription writing support, functioning as a complementary tool to existing EMR systems rather than a replacement.
The platform's core offering includes comprehensive drug information covering over 3,300 brand-name and generic medications, including dosing guidelines, safety information, contraindications, and drug-drug interaction checking. The premium version (Epocrates Plus) adds enhanced features including alternative medication suggestions, disease information for over 600 conditions, diagnostic tools, and lab interpretation guides. Epocrates is deployed primarily as a mobile application for iOS and Android devices, with a web-based interface also available, enabling clinicians to access critical information at the point of care.
Epocrates targets individual physicians and small to mid-sized practices across multiple specialties, particularly those seeking clinical decision support to augment their primary EMR systems. The platform is especially popular among primary care physicians, hospitalists, and residents who require rapid access to drug information during patient encounters. Integration with athenahealth's ecosystem provides enhanced interoperability for practices using athenaOne, though Epocrates functions as a standalone tool compatible with any EMR system.
Key differentiators include its established market presence with decades of clinical content curation, extensive drug database updated daily, and user-friendly mobile interface designed for rapid information retrieval. The platform includes formulary information from major payers, enabling providers to make cost-effective prescribing decisions. Epocrates also offers electronic prescribing capabilities through Surescripts integration, though this functionality is more limited compared to comprehensive EMR-integrated e-prescribing modules.
The business model centers on a freemium approach, with basic drug reference available at no cost and premium features requiring annual subscription. This accessibility has driven widespread adoption, particularly among medical students and residents. However, Epocrates should be understood as a clinical reference and decision support tool rather than a practice management or comprehensive EMR solution, serving as an adjunct to rather than replacement for full-featured electronic health record systems.
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Clinical Decision Support
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Data Breach Information
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HHS Breach PortalA breach at a facility using Epocrates, Inc. does not imply the EMR system was the cause. Breaches can result from many factors including human error, phishing, and physical theft.
Recent Health IT Regulatory Updates
Federal healthcare regulation updates from eCFR
Updated ONC certification criteria for health IT systems including new interoperability requirements under the 21st Century Cures Act.
What this means for you: EHR vendors must meet updated certification criteria. Practices should verify their EMR vendor's compliance status.
Civil monetary penalties for information blocking by health IT developers, health information networks, and health information exchanges are now enforceable under the 21st Century Cures Act.
What this means for you: EHR vendors and health networks can no longer restrict patient access to health data without a qualifying exception. Patients can report suspected information blocking to ONC.
Source: eCFR (Electronic Code of Federal Regulations) | Last updated: 3/24/2026
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