First Databank
by First Databank
First Databank is an electronic health record (EHR) and practice management solution for ambulatory care settings. The system supports outpatient documentation, scheduling, billing, and patient engagement for physician practices and clinics.
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- Ambulatory
- Category
- Active
- Status
- 590 monthly
- Search Interest
- Cloud
- Deployment
Founder & CEO
First Databank is an electronic health record (EHR) and practice management solution for ambulatory care settings. The system supports outpatient documentation, scheduling, billing, and patient engagement for physician practices and clinics.
Category
Status
Search Interest
Deployment
Platform Overview
What is First Databank?
First Databank (FDB) is not a traditional EMR/EHR vendor but rather the leading provider of clinical drug knowledge bases and medication decision support solutions that power medication management within healthcare IT systems. Founded in 1977, FDB serves as the pharmaceutical intelligence backbone for over 4,500 healthcare organizations and technology vendors globally. Rather than competing with EMR systems, FDB provides the critical drug data and clinical decision support infrastructure that enables EMRs, pharmacy systems, and clinical applications to deliver safe, effective medication management.
FDB's core offering consists of comprehensive drug databases covering medications available in the United States and 30+ international markets. These databases include detailed drug monographs, dosing guidelines, interaction screening algorithms, allergy checking, duplicate therapy detection, clinical formulations, and pricing information. The company's flagship products include FDB MedKnowledge for medication information, FDB AlertSpace for clinical screening, and FDB Vela for medication decision support. FDB processes over 5 billion clinical screenings annually through its integrated systems.
What distinguishes FDB from competitors like Wolters Kluwer (Medi-Span), Elsevier (Gold Standard), and Micromedex is its deep integration ecosystem and continuous content updates. FDB maintains partnerships with virtually every major EMR vendor including Epic, Cerner, Meditech, Allscripts, and athenahealth, embedding its drug knowledge directly into clinical workflows. The company employs over 100 pharmacists, physicians, and clinical experts who review and update content continuously, ensuring currency with FDA approvals, drug recalls, and emerging safety concerns.
FDB targets the entire healthcare IT ecosystem rather than specific practice sizes. Its customers range from individual pharmacies to large health systems, PBMs, HIEs, and software vendors. The company operates on an enterprise licensing model where pricing is determined by integration scope, user volume, and modules selected. Implementation typically involves API integration or database licensing rather than traditional software deployment.
FDB's market position is strengthened by regulatory compliance capabilities, supporting EPCS requirements, Surescripts connectivity, and meaningful use criteria. The company has expanded beyond foundational drug data into areas like precision medicine, genomic-guided prescribing through FDB Illuminate, and social determinants of health integration. With healthcare IT vendors increasingly requiring validated, continuously updated drug content to meet safety and regulatory standards, FDB occupies a critical but often invisible infrastructure role in the healthcare technology stack.
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Capabilities
First Databank Features
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Connectivity
Integrations
EMR/EHR Systems
Pharmacy/eRx
Clinical Decision Support
HIE/Interoperability
Population Health
Evaluation
First Databank Pros & Cons
Advantages
- Designed for ambulatory workflow efficiency
- Integrated practice management reduces administrative burden
- Patient portal enhances engagement and communication
- E-prescribing streamlines medication management
Limitations
- May require training to optimize for your specialty
- Integration with hospital systems may require additional configuration
- Pricing varies by practice size and feature set
- Implementation timeline depends on practice complexity
Community Sentiment: First Databank
medium confidenceBest For
Mid-to-large healthcare organizations and health systems requiring comprehensive medication databases with strong clinical decision support integrated into their existing EMR infrastructure
May Not Be Ideal For
Very small ambulatory practices with limited prescription volumes or organizations lacking technical resources for implementation and ongoing optimization
What Users Praise
- +Healthcare organizations consistently highlight the comprehensiveness and clinical accuracy of the drug database, which supports medication safety initiatives
- +Users appreciate the regular content updates that keep formulary information current with minimal manual intervention required
- +Integration capabilities with major EMR platforms receive positive feedback for reducing medication errors through decision support
- +The drug interaction screening functionality is frequently mentioned as strong and clinically relevant
Common Concerns
- -Implementation complexity and the technical expertise required for initial configuration are cited as barriers, particularly for smaller organizations
- -Pricing structure concerns emerge frequently, with users noting that costs can escalate as organizational needs expand
- -Some users report that the volume of clinical alerts can lead to alert fatigue without careful customization
- -Customer support responsiveness receives mixed feedback, with some organizations reporting delays in technical issue resolution
Specialty-Specific Insights
pharmacy
Pharmacy professionals note strong clinical content for formulary management but indicate that customization for institution-specific protocols requires significant effort
Switching Patterns
Why practices switch TO First Databank:
- Healthcare systems adopt First Databank when seeking more comprehensive clinical drug content than their existing solution provides
- Organizations switching to First Databank frequently cite the need for better medication decision support and drug interaction screening
Why practices switch FROM First Databank:
- Smaller practices occasionally move away citing cost considerations relative to their prescription volume and organizational size
- Some organizations switch to alternatives when seeking more streamlined alert systems with less customization required out-of-the-box
Based on analysis of: Healthcare IT forums, Published vendor reviews on healthcare technology platforms, Healthcare industry publications, Professional healthcare IT community discussions. Last researched: February 2026. This is original editorial analysis by MedicalRecords.com, not reproduced content.
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Common Questions
Frequently Asked Questions
Is First Databank HIPAA compliant?
Yes, First Databank is designed to be HIPAA compliant with security features including access controls, audit logs, encryption, and BAA agreements.
Does First Databank support e-prescribing?
First Databank includes e-prescribing (eRx) capabilities including EPCS for controlled substances in supported states.
Can First Databank integrate with labs?
First Databank offers lab integration capabilities to receive results electronically and streamline clinical workflows.
Does First Databank have a patient portal?
First Databank includes a patient portal allowing patients to access their health records, schedule appointments, and communicate with providers.
What size practices use First Databank?
First Databank serves a range of practice sizes from solo practitioners to large multi-provider groups, with pricing and features that scale accordingly.
Vendor Information
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- First Databank
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Security & Data Breach History
Breaches reported at facilities using First Databank
No matched breaches found
No data breaches in the HHS breach portal have been matched to facilities tracked as using First Databank (0 facilities tracked).
Source: HHS Breach Portal | Matched via hospital EMR records
HHS Breach PortalBreach matching is based on hospital-EMR assignments in our database. A breach at a facility using First Databank does not imply the EMR system was the cause. Breaches can result from many factors including human error, phishing, and physical theft.
Recent Health IT Regulatory Updates
Federal healthcare regulation updates from eCFR
Updated ONC certification criteria for health IT systems including new interoperability requirements under the 21st Century Cures Act.
What this means for you: EHR vendors must meet updated certification criteria. Practices should verify their EMR vendor's compliance status.
Civil monetary penalties for information blocking by health IT developers, health information networks, and health information exchanges are now enforceable under the 21st Century Cures Act.
What this means for you: EHR vendors and health networks can no longer restrict patient access to health data without a qualifying exception. Patients can report suspected information blocking to ONC.
Source: eCFR (Electronic Code of Federal Regulations) | Last updated: 3/24/2026
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