ACTH (adrenocorticotropic hormone) is a hormone produced by the pituitary gland, located below the brain. ACTH activates glands on the kidneys (adrenal glands) to make cortisol, a substance that helps the body deal with stress.
When cortisol levels in the blood rise, the ACTH levels in a healthy person normally fall in response. When cortisol levels decrease, ACTH levels normally rise.
Current as of: November 6, 2018
Author: Healthwise Staff
Medical Review:Adam Husney, MD – Family Medicine & E. Gregory Thompson, MD – Internal Medicine & Kathleen Romito, MD – Family Medicine & Alan C. Dalkin, MD – Endocrinology and Metabolism