Angiotensin-Converting Enzyme (ACE) Inhibitors for High Blood Pressure
How It Works
Angiotensin-converting enzyme (ACE)
inhibitors block an needed to form a substance that narrows blood
vessels. As a result, blood vessels relax and widen, making it easier for blood
to flow through the vessels, which reduces . These medicines also
increase the release of water and sodium to the urine, which also lowers .
can be used alone or in combination with
a diuretic or other medicines.
Why It Is Used
These medicines are used alone for
high blood pressure, or they are used with other
medicines such as a diuretic.
heart attack, because the medicine helps reduce the workload on the heart. are a good choice for people who have had a
diabetes, because this medicine does not affect blood sugar
levels and may help protect the . If you have , you may take these medicines if you do not have high but have small amounts of in your urine (microalbuminuria), an early sign of kidney damage. are a good choice for people who have
- footnote 1 may also help to prevent a or stroke.
How Well It Works
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask yourabout the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
- Usually the benefits of the medicine are more important than any minor side effects.
- Side effects may go away after you take the medicine for a while.
- If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.
Call 911 or other emergency services right away if you have:
- Trouble breathing.
- of your face, lips, tongue, or throat.
Call your doctor if you have:
- Irregular heartbeats (this could be caused by too much in your blood).
- Dizziness or lightheadedness or fainting.
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug
Reference is not available in all systems.)
What To Think About
ACE inhibitor cough
A cough is one of the most
common side effects of . But most people do not get a cough. The cough tends to be a minor
problem for most people who have it. They feel that they can live with it in exchange for the benefits of this medicine.
If you take an ACE inhibitor and have a problem with coughing, talk with your doctor. Your cough may be caused by something else, like a cold. Do not stop taking your medicine unless your doctor tells you to.
If you have a cough that is a problem for you, then your doctor might give you an
cause a cough.
Interactions with other medicines
may interact with other medicines
nonsteroidal anti-inflammatory drugs (NSAIDs),
antacids, potassium supplements, certain , and lithium. If you are
taking one of these medicines, talk with your doctor before you take an .
For tips on takingmedicine, see:
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant. If you need to use this medicine, talk to your doctor about how you can prevent.
You may have regular blood tests to monitor how the medicine is working in your body. Your doctor will likely let you know when you need to have the tests.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Current as of:
October 5, 2017