Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, and internal organsâ€”especially the esophagus, kidneys, and digestive tractâ€”is replaced with scar tissue. This change causes the tissues to become stiff and the muscles to not work as well.
ByHealthwise StaffPrimary Medical ReviewerAdam Husney, MD - Family MedicineMartin J. Gabica, MD - Family MedicineKathleen Romito, MD - Family MedicineSpecialist Medical ReviewerPeter J. Kahrilas, MD - Gastroenterology